The following Scotts owned slaves in 1850. Oddly enough, I couldn't find any familes named Scott recorded as MS slaveowners in 1860.

Name of Slave Owner Home in 1850
(City,County,State) View Image

Ann Scott Not Stated, Adams, Mississippi
R T Scott Eastern Division, Chickasaw, Mississippi
William A Scott Eastern Division, Chickasaw, Mississippi
Margaret Scott Subdivision 23, Choctaw, Mississippi
A T Scott Western Division, Choctaw, Mississippi
Andrew Scott Western Division, Choctaw, Mississippi
Robert B Scott District 4, Claiborne, Mississippi
Jeff E Scott District 5, Claiborne, Mississippi
William Scott Not Stated, Copiah, Mississippi
F D Scott Northern Division, DeSoto, Mississippi
Benjn f Scott Southern Division, DeSoto, Mississippi
Nathaniel Scott Southern Division, DeSoto, Mississippi
Nathl Scott Southern Division, DeSoto, Mississippi
Samuel C Scott Southern Division, DeSoto, Mississippi
Samuel C Scott Southern Division, DeSoto, Mississippi
Gabriel B Scott Not Stated, Franklin, Mississippi
James M Scott Not Stated, Franklin, Mississippi
Joseph Scott Not Stated, Franklin, Mississippi
Thomas Scott Not Stated, Franklin, Mississippi
Thomas Scott Not Stated, Franklin, Mississippi
Thomas M Scott Not Stated, Franklin, Mississippi
Charles Scott Not Stated, Hinds, Mississippi
Sidney S Scott Not Stated, Hinds, Mississippi
D Scott Dark Corner, Holmes, Mississippi
A J Scott Not Stated, Jefferson, Mississippi
Isaac Scott Not Stated, Jefferson, Mississippi
Isaac Scott Not Stated, Jefferson, Mississippi
Isaac Scott Not Stated, Jefferson, Mississippi
Jane Scott Not Stated, Jefferson, Mississippi
John Scott Not Stated, Jefferson, Mississippi
S Scott Not Stated, Jefferson, Mississippi
S Scott Not Stated, Jefferson, Mississippi
Thomas Scott Not Stated, Jefferson, Mississippi
Wm Scott Not Stated, Jefferson, Mississippi
Wm F Scott Not Stated, Jefferson, Mississippi
Charles C Scott Not Stated, Kemper, Mississippi
F T Scott Not Stated, Kemper, Mississippi
Robt T Scott Not Stated, Lafayette, Mississippi
J T Scott Beat 2, Leake, Mississippi
Joseph Scott Not Stated, Lowndes, Mississippi
James H Scott Not Stated, Madison, Mississippi
John D Scott Not Stated, Madison, Mississippi
John D Scott Not Stated, Madison, Mississippi
Thomas M Scott Not Stated, Madison, Mississippi
Alexander B Scott Northern Division, Marshall, Mississippi
John Scott Western Division, Monroe, Mississippi
William Scott Western Division, Monroe, Mississippi
Geo N Scott Not Stated, Neshoba, Mississippi
R A Scott Not Stated, Noxubee, Mississippi
William Scott Not Stated, Pontotoc, Mississippi
Romulus Scott Not Stated, Rankin, Mississippi
Nat Scott District 2, Tippah, Mississippi
Samuel Scott Division 3, Tippah, Mississippi
H Scott District 4, Tishomingo, Mississippi
Robt B Scott Not Stated, Warren, Mississippi
Thomas J Scott Vicksburg, Warren, Mississippi
John A Scott Not Stated, Washington, Mississippi
Thos F Scott Not Stated, Wilkinson, Mississippi
Samuel Scott North of the Yalobusha River, Yalobusha, Mississippi
Burwell Scott Not Stated, Yazoo, Mississippi
Margt c Scott Not Stated, Yazoo, Mississippi
Margt c Scott Not Stated, Yazoo, Mississippi
W P Scott Not Stated, Yazoo, Mississippi