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African American DNA Research Forum

Re: Question about DNA Admixture Tests

I've thought about the admixture tests some since my Gram, Mom, sister, & I did them last year. I'm guessing that with the autosomal DNA tests, they may look at many samples from the regions representing Sub-Saharan African, Native American, European,and East Asian populations. Then they must have a way of saying that at a particular locus certain combinations of the nucleotides GCAT appear more often within groups in the 4 regions, and they assign the percentages based on the region-matching combinations. (I'm guessing, but this could lead to confusion if you've got lots of mixes ancestrally.)

Suppose they had a position that predominated TT among Native Americans, AA among Sub-Saharan people, and TA among Europeans. Hypothetical test person gets the result TA and that gets calculated into the European percentage. However, they got a T from the 1st parent and an A from the 2nd parent. We still don't know if the position for 1st parent is TT or TA, or if the second parent's position is TA or AA. So, it would appear that the Sub-Saharan African Ancestry was "lost," but it really isn't. Perhaps I'll write DNAPrint Genomics and ask how they really assign base pairs to the regions.

Sonia

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18 Dec 2002 :: 14 Nov 2008
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