Indeed AfriGeneas does work!
Many thanx to Art, Selma, Angela, Arlene, Lisa, Vicky, Regina, Paul, David, and ALL Volunteers.
I posted this request for help and within 1/2 hour I had received an email from AfriGeneas regular Selinva with the information my firend was seeking.
Yes, the record confirmed the couple were his grandparents. The "clenching" information was the birth location and the named parents of the bride. This ancestor of my friend (bride) was a descendant of early FPOC settlers in Ohio, dating back to the mid 1830's in Mercer County, Ohio.
We saved a copy of the image of this record and forwarded it to my friend.
Thanks AfriGeneas and Selinva.